tigerd

September 12th, 2020 at 3:01 PM ^

Yea, God forbid you have a positive comment about it moving forward as that's a recipe for getting negged on this all too often covid doomsday forum. Sitting here watching ND and Duke play with 100% of their players in tow, fans in the stands, etc. and hating the fact that the Big 10 is just sitting on the sidelines. Neg away folks as I can't tell you enough that I could not care less. If it makes you feel better to neg those that have a contrary opinion to yours about what's going on,have at it.

Joined: 11/12/2016

MGoPoints: 6470

BoFan

September 12th, 2020 at 3:45 PM ^

No one on here would be negative about progress on a Vaccine. That’s a completely absurd and inflammatory statement.  
 

There is an exception.  The anti-vaxxers conspiracy theorists would be the only ones opposed to vaccine progress.  Hopefully we won’t here from them. 

Joined: 03/09/2012

MGoPoints: 20046

Princetonwolverine

September 12th, 2020 at 4:30 PM ^

Imagine you are a top high school football player with offers from Michigan,  SEC, ACC and Big12 teams. Your high school is playing. You want to play.with a goal of playing in the NFL.

Where are you going to play in college?

Joined: 10/10/2010

MGoPoints: 14174

Blue Vet

September 12th, 2020 at 4:21 PM ^

Thanks for the post. But it does make me wonder though if we should just get live feeds of labs, with non-stop commentators to keep us all up-to-date on science stuff.

Joined: 05/08/2012

MGoPoints: 71556

Aspyr

September 12th, 2020 at 5:34 PM ^

FYI UK trial to resume not the US one yet. AstraZeneca spokesman said a woman had developed severe neurological symptoms, a rare inflammation of the spinal cord. That doesn't seem like a trivial issue but I guess we will see as time goes by.

Joined: 06/21/2012

MGoPoints: 2576

Sopwith

September 12th, 2020 at 5:59 PM ^

They did the right thing and evidently it's been determined the complication, which was serious, is unrelated to the vaccine unless it starts popping up in other patients.

Worth bearing in mind what they're testing. While it's important for any vaccine in Phase III to pause when there is a significant adverse event, it's especially important for this particular one from Oxford/AZ.  This is a adenovirus vector, which means they are taking SARS-CoV-2 genes (specifically the famous spike protein) and transporting them into patients by infecting the patients with a different virus isolated from chimps and closely related to the common cold in the natural world.

Adenovirus-based vectors got a bad name because of a notorious gene therapy trial in 1998 that led to the death of a healthy volunteer at UPenn (Google "Jesse Gelsinger"). The scrutiny led to many safety improvements since then (after years of freezing clinical trials for all gene therapies) but there will always be more scrutiny on adenoviral vectors than just about any other way of delivering genes/vaccines. 

Joined: 06/29/2010

MGoPoints: 61153